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Fluoride ion promoted deprotection and transesterification in nucleotide triesters.

Tetrabutylammonium fluoride will remove phenyl, trichloroethyl and cyanoethyl groups from nucleotides. In addition to the desired nucleotide products other results including chain cleavage, phosphofluoridates and cyanoethylated thymidine units may be obtained depending on the conditions used. Fluori...

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Bibliografiske detaljer
Main Authors: Ogilvie, K K, Beaucage, S L
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC328057/
https://ncbi.nlm.nih.gov/pubmed/503847
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