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Effects of α-Adrenoceptor Antagonists on ABCG2/BCRP-Mediated Resistance and Transport

Acquired resistance of cancer cells to various chemotherapeutic agents is known as multidrug resistance, and remains a critical factor in the success of cancer treatment. It is necessary to develop the inhibitors for multidrug resistance. The aim of this study was to examine the effects of eight α-a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Takara, Kohji, Yamamoto, Kazuhiro, Matsubara, Mika, Minegaki, Tetsuya, Takahashi, Minoru, Yokoyama, Teruyoshi, Okumura, Katsuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280247/
https://ncbi.nlm.nih.gov/pubmed/22355323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030697
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