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Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics

Adenine triphosphate (ATP)-binding cassette (ABC) transporter proteins, such as ABCB1/P-glycoprotein (P-gp) and ABCG2/breast cancer resistance protein (BCRP), transport various structurally unrelated compounds out of cells. ABCG2/BCRP is referred to as a “half-type” ABC transporter, functioning as a...

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Detalhes bibliográficos
Main Authors: Noguchi, Kohji, Katayama, Kazuhiro, Sugimoto, Yoshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921828/
https://ncbi.nlm.nih.gov/pubmed/24523596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S38295
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