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The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids
BACKGROUND AND PURPOSE: Cannabinoids are used therapeutically for the palliation of the adverse side effects associated with cancer chemotherapy. However, cannabinoids also inhibit both the activity and expression of the multidrug transporter, P-glycoprotein in vitro. Here we address the interaction...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2190019/ https://ncbi.nlm.nih.gov/pubmed/17906686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707467 |
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