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The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids

BACKGROUND AND PURPOSE: Cannabinoids are used therapeutically for the palliation of the adverse side effects associated with cancer chemotherapy. However, cannabinoids also inhibit both the activity and expression of the multidrug transporter, P-glycoprotein in vitro. Here we address the interaction...

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Bibliografiska uppgifter
Huvudupphovsmän: Holland, M L, Lau, D T T, Allen, J D, Arnold, J C
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190019/
https://ncbi.nlm.nih.gov/pubmed/17906686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707467
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