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Subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances
BACKGROUND: Driven essentially by random genetic drift, subfunctionalization has been identified as a possible non-adaptive mechanism for the retention of duplicate genes in small-population species, where widespread deleterious mutations are likely to cause complementary loss of subfunctions across...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280233/ https://ncbi.nlm.nih.gov/pubmed/22168623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-604 |
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