Chargement en cours...

Subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances

BACKGROUND: Driven essentially by random genetic drift, subfunctionalization has been identified as a possible non-adaptive mechanism for the retention of duplicate genes in small-population species, where widespread deleterious mutations are likely to cause complementary loss of subfunctions across...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Fernández, Ariel, Tzeng, Yun-Huei, Hsu, Sze-Bi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280233/
https://ncbi.nlm.nih.gov/pubmed/22168623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-604
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!