Decreased expression of 17β-hydroxysteroid dehydrogenase type 1 is associated with DNA hypermethylation in colorectal cancer located in the proximal colon

BACKGROUND: The importance of 17β-estradiol (E2) in the prevention of large bowel tumorigenesis has been shown in many epidemiological studies. Extragonadal E2 may form by the aromatase pathway from androstenedione or the sulfatase pathway from estrone (E1) sulfate followed by E1 reduction to E2 by...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Rawłuszko, Agnieszka Anna, Horbacka, Karolina, Krokowicz, Piotr, Jagodziński, Paweł Piotr
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280200/
https://ncbi.nlm.nih.gov/pubmed/22176788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-522
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