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Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast

BACKGROUND: The uptake of drugs into cells has traditionally been considered to be predominantly via passive diffusion through the bilayer portion of the cell membrane. The recent recognition that drug uptake is mostly carrier-mediated raises the question of which drugs use which carriers. RESULTS:...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lanthaler, Karin, Bilsland, Elizabeth, Dobson, Paul D, Moss, Harry J, Pir, Pınar, Kell, Douglas B, Oliver, Stephen G
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280192/
https://ncbi.nlm.nih.gov/pubmed/22023736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-70
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