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Haploinsufficiency and the sex chromosomes from yeasts to humans
BACKGROUND: Haploinsufficient (HI) genes are those for which a reduction in copy number in a diploid from two to one results in significantly reduced fitness. Haploinsufficiency is increasingly implicated in human disease, and so predicting this phenotype could provide insights into the genetic mech...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058074/ https://ncbi.nlm.nih.gov/pubmed/21356089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-15 |
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