Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

We have developed a robust, fully automated anti-parasitic drug-screening method that selects compounds specifically targeting parasite enzymes and not their host counterparts, thus allowing the early elimination of compounds with potential side effects. Our yeast system permits multiple parasite ta...

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Bibliografske podrobnosti
Main Authors: Bilsland, Elizabeth, Sparkes, Andrew, Williams, Kevin, Moss, Harry J., de Clare, Michaela, Pir, Pınar, Rowland, Jem, Aubrey, Wayne, Pateman, Ron, Young, Mike, Carrington, Mark, King, Ross D., Oliver, Stephen G.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603448/
https://ncbi.nlm.nih.gov/pubmed/23446112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.120158
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