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Age and diagnostic performance of Alzheimer disease CSF biomarkers
OBJECTIVES: Core CSF changes in Alzheimer disease (AD) are decreased amyloid β(1–42), increased total tau, and increased phospho-tau, probably indicating amyloid plaque accumulation, axonal degeneration, and tangle pathology, respectively. These biomarkers identify AD already at the predementia stag...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Lippincott Williams & Wilkins
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280049/ https://ncbi.nlm.nih.gov/pubmed/22302554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182477eed |
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