DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function

Previous studies demonstrated decreased levels of DJ-1 and α-synuclein (αSYN) in human cerebrospinal fluid (CSF) in patients with Parkinson’s disease (PD), but neither marker correlated with PD severity, raising the possibility that they may be excellent progression markers during early or preclinic...

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Autors principals: Shi, Min, Furay, Amy, Sossi, Vesna, Aasly, Jan O., Armaly, Jeff, Wang, Yu, Wszolek, Zbigniew K., Uitti, Ryan J., Hasegawa, Kazuko, Yokoyama, Teruo, Zabetian, Cyrus P., Leverenz, James B., Stoessl, A. Jon, Zhang, Jing
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279603/
https://ncbi.nlm.nih.gov/pubmed/22019052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.09.015
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