Serotonin transporter binding and motor onset of Parkinson's disease in asymptomatic LRRK2 mutation carriers: a cross-sectional study

BACKGROUND: Patients with Parkinson’s Disease (PD) may exhibit premotor neurochemical changes in dopaminergic (DA) and nondopaminergic systems. Using positron emission tomography (PET), we studied participants with leucine-rich repeat kinase 2 (LRRK2) mutations and with sporadic PD to assess whether...

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Detaylı Bibliyografya
Yayımlandı:Lancet Neurol
Asıl Yazarlar: Wile, Daryl J, Agarwal, Pankaj A, Schulzer, Michael, Mak, Edwin, Dinelle, Katherine, Shahinfard, Elham, Vafai, Nasim, Hasegawa, Kazuko, Zhang, Jing, McKenzie, Jessamyn, Neilson, Nicole, Strongosky, Audrey, Uitti, Ryan J, Guttman, Mark, Zabetian, Cyrus P, Ding, Yu-Shin, Adam, Mike, Aasly, Jan, Wszolek, Zbigniew K, Farrer, Matthew, Sossi, Vesna, Stoessl, A Jon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477770/
https://ncbi.nlm.nih.gov/pubmed/28336296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(17)30056-X
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