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Specific inhibition of capped mRNA translation in vitro by m7G5'pppp5'G and m7G5'pppp5'm7G.

A unique set of diguanosine cap analogues containing a 5'-5' tetraphosphate linkage instead of the normal triphosphate was synthesized by chemical methylation of G5'pppp5'G. Both 7-methylguanosine products, m7G5'pppp5'G and m7G5'pppp5'm7G, acted as potent inhi...

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Detalhes bibliográficos
Main Authors: Sasavage, N L, Friderici, K, Rottman, F M
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC327960/
https://ncbi.nlm.nih.gov/pubmed/493116
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