Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy

OBJECTIVE: A multicenter, controlled trial showed that early blockade of the renin-angiotensin system in patients with type 1 diabetes and normoalbuminuria did not retard the progression of nephropathy, suggesting that other mechanism(s) are involved in the pathogenesis of early diabetic nephropathy...

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Autors principals: Li, Jinhua, Qu, Xinli, Yao, Jun, Caruana, Georgina, Ricardo, Sharon D., Yamamoto, Yasuhiko, Yamamoto, Hiroshi, Bertram, John F.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2010
Matèries:
Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279546/
https://ncbi.nlm.nih.gov/pubmed/20682692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1631
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