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Cultured Subventricular Zone Progenitor Cells Transduced with Neurogenin-2 Become Mature Glutamatergic Neurons and Integrate into the Dentate Gyrus

We have previously shown that transplantation of immature DCX+/NeuN+/Prox1+ neurons (found in the neonatal DG), but not undifferentiated neuronal progenitor cells (NPCs) from ventral subventricular zone (SVZ), results in neuronal maturation in vivo within the dentate niche. Here we investigated whet...

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Hlavní autoři: Chen, Xia, Lepier, Alexandra, Berninger, Benedikt, Tolkovsky, Aviva M., Herbert, Joe
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279376/
https://ncbi.nlm.nih.gov/pubmed/22348101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031547
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