Cultured Subventricular Zone Progenitor Cells Transduced with Neurogenin-2 Become Mature Glutamatergic Neurons and Integrate into the Dentate Gyrus

We have previously shown that transplantation of immature DCX+/NeuN+/Prox1+ neurons (found in the neonatal DG), but not undifferentiated neuronal progenitor cells (NPCs) from ventral subventricular zone (SVZ), results in neuronal maturation in vivo within the dentate niche. Here we investigated whet...

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Autors principals: Chen, Xia, Lepier, Alexandra, Berninger, Benedikt, Tolkovsky, Aviva M., Herbert, Joe
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279376/
https://ncbi.nlm.nih.gov/pubmed/22348101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031547
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