TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions

BACKGROUND: The TRIM5 proteins are cellular restriction factors that prevent retroviral infection in a species-specific manner. Multiple experiments indicate that restriction activity requires accessory host factors, including E2-enzymes. To better understand the mechanism of restriction, we conduct...

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Bibliografiske detaljer
Main Authors: Lukic, Zana, Hausmann, Stéphane, Sebastian, Sarah, Rucci, Justin, Sastri, Jaya, Robia, Seth L, Luban, Jeremy, Campbell, Edward M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279310/
https://ncbi.nlm.nih.gov/pubmed/22078707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-93
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