Intracoronary Levosimendan during Ischemia Prevents Myocardial Apoptosis

Background: Levosimendan is a calcium sensitizer that has been shown to prevent myocardial contractile depression in patients post cardiac surgery. This drug exhibits an anti-apoptotic property; however, the underlying mechanism remains elusive. In this report, we characterized the myocardial protec...

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Bibliographic Details
Main Authors: Malmberg, Markus, Vähäsilta, Tommi, Saraste, Antti, Koskenvuo, Juha W., Pärkkä, Jussi P., Leino, Kari, Laitio, Timo, Stark, Christoffer, Heikkilä, Aira, Saukko, Pekka, Savunen, Timo
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278776/
https://ncbi.nlm.nih.gov/pubmed/22347864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00017
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