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Pegylated and liposomal doxorubicin is associated with high mortality and causes limited cardiotoxicity in mice
OBJECTIVE: We wanted to determine the impact of different doses of a pegylated and liposomal formulation of the cardiotoxic drug doxorubicin on cardiac function, fibrosis and survival in mice. The drug causes myocardial damage by producing reactive oxygen species, mitochondrial damage and lipid pero...
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| Udgivet i: | BMC Res Notes |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5822632/ https://ncbi.nlm.nih.gov/pubmed/29467032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3260-6 |
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