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Mutational tipping points for switching protein folds and functions

While disordered to ordered rearrangements are relatively common, the ability of proteins to switch from one ordered fold to a completely different fold is generally regarded as rare and few fold switches have been characterized. Here, in a designed system, we examine the mutational requirements for...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: He, Yanan, Chen, Yihong, Alexander, Patrick A., Bryan, Philip N., Orban, John
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278708/
https://ncbi.nlm.nih.gov/pubmed/22325777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.11.018
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