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Subdomain Interactions Foster the Design of Two Protein Pairs with ∼80% Sequence Identity but Different Folds
Metamorphic proteins, including proteins with high levels of sequence identity but different folds, are exceptions to the long-standing rule-of-thumb that proteins with as little as 30% sequence identity adopt the same fold. Which topologies can be bridged by these highly identical sequences remains...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286614/ https://ncbi.nlm.nih.gov/pubmed/25564862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.073 |
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