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Defining a role for sphingosine kinase 1 in p53-dependent tumors
p53 is a crucial tumor suppressor that is mutated or deleted in a majority of cancers. Exactly how p53 prevents tumor progression has proved elusive for many years; however, this information is crucial to define targets for chemotherapeutic development that can effectively restore p53 function. Bioa...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278571/ https://ncbi.nlm.nih.gov/pubmed/21765468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.302 |
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