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Female CGG Knock-In Mice Modeling the Fragile X Premutation are Impaired on a Skilled Forelimb Reaching Task

The fragile X premutation is a tandem CGG trinucleotide repeat expansion in the Fragile X Mental Retardation 1 (FMR1) gene between 55 and 200 repeats in length. A CGG knock-in (CGG KI) mouse has been developed that models the neuropathology and cognitive deficits reported in fragile X premutation ca...

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Bibliografiset tiedot
Päätekijät: Diep, Amanda A., Hunsaker, Michael R., Kwock, Richard, Kim, Kyoungmi, Willemsen, Rob, Berman, Robert F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278548/
https://ncbi.nlm.nih.gov/pubmed/22202169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2011.12.006
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