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Female CGG Knock-In Mice Modeling the Fragile X Premutation are Impaired on a Skilled Forelimb Reaching Task
The fragile X premutation is a tandem CGG trinucleotide repeat expansion in the Fragile X Mental Retardation 1 (FMR1) gene between 55 and 200 repeats in length. A CGG knock-in (CGG KI) mouse has been developed that models the neuropathology and cognitive deficits reported in fragile X premutation ca...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278548/ https://ncbi.nlm.nih.gov/pubmed/22202169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2011.12.006 |
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