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SCF ubiquitin ligases in the maintenance of genome stability
In response to genotoxic stress, eukaryotic cells activate the DNA damage response (DDR), a series of pathways that coordinate cell cycle arrest and DNA repair to prevent deleterious mutations. In addition, cells possess checkpoint mechanisms that prevent aneuploidy by regulating the number of centr...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278546/ https://ncbi.nlm.nih.gov/pubmed/22099186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.10.004 |
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