Common variants in ABCB1, ABCC2 and ABCG2 genes and clinical outcomes among women with advanced stage ovarian cancer treated with platinum and taxane-based chemotherapy: a Gynecologic Oncology Group study

PURPOSE: Efflux transporters of the ATP-binding cassette (ABC) family are major determinants of chemoresistance in tumor cells. This study examined associations between functional variants in ABCB1, ABCC2 and ABCG2 genes and clinical outcomes in patients with epithelial ovarian/primary peritoneal ca...

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Hlavní autoři: Tian, Chunqiao, Ambrosone, Christine B, Darcy, Kathleen M, Krivak, Thomas C, Armstrong, Deborah K., Bookman, Michael A, Davis, Warren, Zhao, Hua, Moysich, Kirsten, Gallion, Holly, DeLoia, Julie A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278512/
https://ncbi.nlm.nih.gov/pubmed/22112610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2011.11.022
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