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Regulation of the let-7a-3 Promoter by NF-κB

Changes in microRNA expression have been linked to a wide array of pathological states. However, little is known about the regulation of microRNA expression. The let-7 microRNA is a tumor suppressor that inhibits cellular proliferation and promotes differentiation, and is frequently lost in tumors....

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Autors principals: Wang, David J., Legesse-Miller, Aster, Johnson, Elizabeth L., Coller, Hilary A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278432/
https://ncbi.nlm.nih.gov/pubmed/22348059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031240
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