let-7 Overexpression Leads to an Increased Fraction of Cells in G(2)/M, Direct Down-regulation of Cdc34, and Stabilization of Wee1 Kinase in Primary Fibroblasts

microRNAs play a critically important role in a wide array of biological processes including those implicated in cancer, neuro-degenerative and metabolic disorders, and viral infection. Although we have begun to understand microRNA biogenesis and function, experimental demonstration of their functio...

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Detalhes bibliográficos
Main Authors: Legesse-Miller, Aster, Elemento, Olivier, Pfau, Sarah J., Forman, Joshua J., Tavazoie, Saeed, Coller, Hilary A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Accelerated Publications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652271/
https://ncbi.nlm.nih.gov/pubmed/19126550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C900002200
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