MicroRNA-let-7a promotes E2F-mediated cell proliferation and NFκB activation in vitro

Epigenetic factors, including altered microRNA (miRNA) expression, may contribute to aberrant immune cell function in systemic lupus erythematosus (SLE). MiRNA-let-7a (let-7a) has been shown to directly alter cell cycle progression and proinflammatory cytokine production. Due to the crucial role of...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Chafin, Cristen B, Regna, Nicole L, Caudell, David L, Reilly, Christopher M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947333/
https://ncbi.nlm.nih.gov/pubmed/24240124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2013.51
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