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MicroRNA-let-7a promotes E2F-mediated cell proliferation and NFκB activation in vitro
Epigenetic factors, including altered microRNA (miRNA) expression, may contribute to aberrant immune cell function in systemic lupus erythematosus (SLE). MiRNA-let-7a (let-7a) has been shown to directly alter cell cycle progression and proinflammatory cytokine production. Due to the crucial role of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947333/ https://ncbi.nlm.nih.gov/pubmed/24240124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2013.51 |
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