Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition

BACKGROUND: Currently, Atypical Teratoid Rhabdoid Tumor (AT/RT) constitutes one of the most difficult to treat malignancies in pediatrics. Hence, new knowledge of potential targets for therapeutics and the development of novel treatment approaches are urgently needed. We have evaluated the presence...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jayanthan, Aarthi, Bernoux, Delphine, Bose, Pinaki, Riabowol, Karl, Narendran, Aru
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Primary Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278350/
https://ncbi.nlm.nih.gov/pubmed/22206574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-44
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