Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition

BACKGROUND: Currently, Atypical Teratoid Rhabdoid Tumor (AT/RT) constitutes one of the most difficult to treat malignancies in pediatrics. Hence, new knowledge of potential targets for therapeutics and the development of novel treatment approaches are urgently needed. We have evaluated the presence...

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Detaylı Bibliyografya
Asıl Yazarlar: Jayanthan, Aarthi, Bernoux, Delphine, Bose, Pinaki, Riabowol, Karl, Narendran, Aru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Primary Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278350/
https://ncbi.nlm.nih.gov/pubmed/22206574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-44
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