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Synthesis, characterization, and in vivo efficacy evaluation of PGG–docetaxel conjugate for potential cancer chemotherapy
AIM: This work is intended to develop and evaluate a biopolymeric poly(L-γ-glutamylglutamine) (PGG)–docetaxel (DTX) conjugate that can spontaneously self-assemble in aqueous solutions to become nanoparticles. METHODS: DTX was covalently attached to hydrophilic PGG by direct esterification, and the c...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278226/ https://ncbi.nlm.nih.gov/pubmed/22334784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S26842 |
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