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Physicochemical properties and biocompatibility of a polymer-paclitaxel conjugate for cancer treatment

BACKGROUND: Poly(L-γ-glutamylglutamine) paclitaxel (PGG-PTX) conjugate is a non-diblock polymeric drug nanoparticle intended to improve the therapeutic index of paclitaxel. The purpose of the present study was to elucidate further the physicochemical properties of PGG-PTX in order to proceed with it...

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Detalhes bibliográficos
Main Authors: Yang, Danbo, Van, Sang, Liu, Jian, Wang, Jing, Jiang, Xinguo, Wang, Yiting, Yu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205149/
https://ncbi.nlm.nih.gov/pubmed/22072890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S25044
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