Design of theranostic nanomedicine (II): synthesis and physicochemical properties of a biocompatible polyphosphazene–docetaxel conjugate

To prepare an efficient theranostic polyphosphazene–docetaxel (DTX) conjugate, a new drug delivery system was designed by grafting a multifunctional lysine ethylester (LysOEt) as a spacer group along with methoxy poly(ethylene glycol) (MPEG) to the polyphosphazene backbone ([NP](n)), and then DTX wa...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Jun, Yong Joo, Park, Jung Hyun, Avaji, Prakash G, Park, Kyung Su, Lee, Kyung Eun, Lee, Hwa Jeong, Sohn, Youn Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538706/
https://ncbi.nlm.nih.gov/pubmed/28794629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S140073
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