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Folate metabolic pathways in Leishmania

Trypanosomatid parasitic protozoans of the genus Leishmania are autotrophic for both folate and unconjugated pteridines. Leishmania salvage these metabolites from their mammalian hosts and insect vectors through multiple transporters. Within the parasite, folates are reduced by a bifunctional DHFR (...

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Bibliografiska uppgifter
Huvudupphovsmän: Vickers, Tim J., Beverley, Stephen M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278214/
https://ncbi.nlm.nih.gov/pubmed/22023442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/bse0510063
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