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Synthesis of human insulin gene. Part I. Development of reversed-phase chromatography in the modified triester method. Its application in the rapid and efficient synthesis of eight deoxyribooligonucleotides fragments constituting human insulin A DNA.

Preparative reversed-phase thin layer chromatography on silanized silica-gel (RP-2 and RP-18) has been developed to purify triester deoxyribooligonucleotides prepared by the modified triester method. The effectiveness of this technique has been demonstrated in the rapid synthesis of eight pure deoxy...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hsiung, H M, Brousseau, R, Michniewicz, J, Narang, S A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1979
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC327778/
https://ncbi.nlm.nih.gov/pubmed/450699
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