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Ring finger protein 146/Iduna is a Poly (ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase

Recent findings suggest that Ring finger protein 146 (RNF146), also called Iduna, have neuroprotective property due to its inhibition of Parthanatos via binding with Poly(ADP-ribose) (PAR). The Parthanatos is a PAR dependent cell death that has been implicated in many human diseases. RNF146/Iduna ac...

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Hlavní autoři: Zhou, Zhi-dong, Chan, Christine Hui-shan, Xiao, Zhi-cheng, Tan, Eng-King
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277779/
https://ncbi.nlm.nih.gov/pubmed/22274711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.6.18356
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