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Ring finger protein 146/Iduna is a Poly (ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase

Recent findings suggest that Ring finger protein 146 (RNF146), also called Iduna, have neuroprotective property due to its inhibition of Parthanatos via binding with Poly(ADP-ribose) (PAR). The Parthanatos is a PAR dependent cell death that has been implicated in many human diseases. RNF146/Iduna ac...

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Detalhes bibliográficos
Main Authors: Zhou, Zhi-dong, Chan, Christine Hui-shan, Xiao, Zhi-cheng, Tan, Eng-King
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277779/
https://ncbi.nlm.nih.gov/pubmed/22274711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.6.18356
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