Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

Ubiquitin mediated protein degradation is crucial for regulation of cell signaling and protein quality control. Poly(ADP-ribose) (PAR) is a cell-signaling molecule that mediates changes in protein function through binding at PAR binding sites. Here we characterize the PAR binding protein, Iduna, and...

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Detalhes bibliográficos
Main Authors: Kang, Ho Chul, Lee, Yun-Il, Shin, Joo-Ho, Andrabi, Shaida A., Chi, Zhikai, Gagné, Jean-Philippe, Lee, Yunjong, Ko, Han Seok, Lee, Byoung Dae, Poirier, Guy G., Dawson, Valina L., Dawson, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161609/
https://ncbi.nlm.nih.gov/pubmed/21825151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108799108
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