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Assessment of Compound Hepatotoxicity Using Human Plateable Cryopreserved Hepatocytes in a 1536-Well-Plate Format

Hepatotoxicity is a major concern for both drug development and toxicological evaluation of environmental chemicals. The assessment of compound-induced hepatotoxicity has traditionally relied on in vivo testing; however, it is being replaced by human in vitro models due to an emphasis on the reducti...

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Detalhes bibliográficos
Main Authors: Moeller, Timothy A., Shukla, Sunita J., Xia, Menghang
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277728/
https://ncbi.nlm.nih.gov/pubmed/22053711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0365
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