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Structural Studies of a Signal Peptide in Complex with Signal Peptidase I Cytoplasmic Domain: the Stabilizing Effect of Membrane-Mimetics on the Acquired Fold

A protein destined for export from the cell cytoplasm is synthesized as a preprotein with an amino-terminal signal peptide. In Escherichia coli, signal peptides that guide preproteins into the SecYEG protein conduction channel are typically subsequently removed by signal peptidase I. To understand t...

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Detalhes bibliográficos
Main Authors: De Bona, Paolo, Deshmukh, Lalit, Gorbatyuk, Vitaliy, Vinogradova, Olga, Kendall, Debra A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277640/
https://ncbi.nlm.nih.gov/pubmed/22113858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23238
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