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Tyrosine Phosphorylation as a Conformational Switch: A CASE STUDY OF INTEGRIN β(3) CYTOPLASMIC TAIL

Reversible protein phosphorylation is vital for many fundamental cellular processes. The actual impact of adding and removing phosphate group(s) is 3-fold: changes in the local/global geometry, alterations in the electrostatic potential and, as the result of both, modified protein-target interaction...

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Autors principals: Deshmukh, Lalit, Meller, Nahum, Alder, Nathan, Byzova, Tatiana, Vinogradova, Olga
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220520/
https://ncbi.nlm.nih.gov/pubmed/21956114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.231951
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