Translating Mendelian and complex inheritance of Alzheimer's disease genes for predicting unique personal genome variants

OBJECTIVE: Although trait-associated genes identified as complex versus single-gene inheritance differ substantially in odds ratio, the authors nonetheless posit that their mechanistic concordance can reveal fundamental properties of the genetic architecture, allowing the automated interpretation of...

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Detalhes bibliográficos
Main Authors: Regan, Kelly, Wang, Kanix, Doughty, Emily, Li, Haiquan, Li, Jianrong, Lee, Younghee, Kann, Maricel G, Lussier, Yves A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2012
Assuntos:
Research and Applications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277633/
https://ncbi.nlm.nih.gov/pubmed/22319180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2011-000656
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