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Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation

The cilium serves as a cellular antenna by coordinating upstream environmental cues with numerous downstream signaling processes that are indispensable for the function of the cell. This role is supported by the revelation that defects of the cilium underlie an emerging class of human disorders, ter...

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Autori principali: Yuan, Shiaulou, Li, Jade, Diener, Dennis R., Choma, Michael A., Rosenbaum, Joel L., Sun, Zhaoxia
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277533/
https://ncbi.nlm.nih.gov/pubmed/22308353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112834109
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