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Addition of oligonucleotides to the 5'-terminus of DNA by T4 RNA ligase.

Bacteriophage T4-induced RNA ligase catalyzes the controlled template-independent addition of RNA to the 5'-phosphoryl end of large DNA molecules. Restriction enzyme-generated fragments of Co1E1 DNA with completely basepaired or cohesive ends and linear single-stranded øX174 viral DNA were all...

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Autors principals: Higgins, N P, Geballe, A P, Cozzarelli, N R
Format: Artigo
Idioma:Inglês
Publicat: 1979
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC327749/
https://ncbi.nlm.nih.gov/pubmed/375192
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