The C allele of JAK2 rs4495487 is an additional candidate locus that contributes to myeloproliferative neoplasm predisposition in the Japanese population

BACKGROUND: Polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) are myeloproliferative neoplasms (MPNs) characterized in most cases by a unique somatic mutation, JAK2 V617F. Recent studies revealed that JAK2 V617F occurs more frequently in a specific JAK2 haplotyp...

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Hauptverfasser: Ohyashiki, Junko H, Yoneta, Masayuki, Hisatomi, Hisashi, Iwabuchi, Tamiko, Umezu, Tomohiro, Ohyashiki, Kazuma
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277458/
https://ncbi.nlm.nih.gov/pubmed/22251709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-6
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