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Inherited predisposition to myeloproliferative neoplasms
Myeloproliferative neoplasms (MPNs) are haematological disorders characterized by an overproduction of mature myeloid cells with a tendency to transform to acute myeloid leukaemia. Clonal proliferation of myeloid progenitor cells is driven by somatically acquired mutations, most notably JAK2 V617F,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3734902/ https://ncbi.nlm.nih.gov/pubmed/23926457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620713489144 |
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