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Rad51 Promoter-Targeted Gene Therapy Is Effective for In Vivo Visualization and Treatment of Cancer
Rad51 protein is overexpressed in a wide range of human cancers. Our previous in vitro studies demonstrated that a construct comprised Rad51 promoter driving expression of the diphtheria toxin A gene (pRad51-diphtheria toxin A (DTA)) destroys a variety of human cancer cell lines, with minimal to no...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2012
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277325/ https://ncbi.nlm.nih.gov/pubmed/22008909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.215 |
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