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Use of the Rad51 promoter for targeted anti-cancer therapy
Rad51 protein, involved in homologous recombination, is overexpressed in a variety of tumors, and its expression is correlated with a poor prognosis. Here we propose to exploit the overexpression of Rad51 in cancer cells to design a Rad51 promoter-based anticancer therapy. On average, Rad51 mRNA and...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634908/ https://ncbi.nlm.nih.gov/pubmed/19106292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807990106 |
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